Cargando…
Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin
Geniposide (GE) is the main bioactive component of Gardeniae Fructus. The hepatotoxicity of geniposide limited clinical application. In order to get a new geniposide derivative that has less hepatotoxicity and still possesses the antidepressant activity, a new C-1 hydroxyl methylation derivative nam...
Autores principales: | Che, Xin, Wang, Meiyu, Wang, Tian, Fan, Huaying, Yang, Mingyan, Wang, Wenyan, Xu, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273916/ https://www.ncbi.nlm.nih.gov/pubmed/27438811 http://dx.doi.org/10.3390/molecules21070923 |
Ejemplares similares
-
Acute and subacute hepatotoxicity of genipin in mice and its potential mechanism
por: Wang, Shuaikang, et al.
Publicado: (2023) -
Antidepressants- and antipsychotics-induced hepatotoxicity
por: Todorović Vukotić, Nevena, et al.
Publicado: (2021) -
Blood-brain barrier permeability and physical exercise
por: Małkiewicz, Marta A., et al.
Publicado: (2019) -
Blood-brain barrier permeability following traumatic brain injury
por: Jungner, M, et al.
Publicado: (2012) -
Biotransformation of Geniposide into Genipin by Immobilized Trichoderma reesei and Conformational Study of Genipin
por: Yang, Yishun, et al.
Publicado: (2018)