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Immobilization of Neutral Protease from Bacillus subtilis for Regioselective Hydrolysis of Acetylated Nucleosides: Application to Capecitabine Synthesis

This paper describes the immobilization of the neutral protease from Bacillus subtilis and its application in the regioselective hydrolysis of acetylated nucleosides, including building blocks useful for the preparation of anticancer products. Regarding the immobilization study, different results ha...

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Detalles Bibliográficos
Autores principales: Bavaro, Teodora, Cattaneo, Giulia, Serra, Immacolata, Benucci, Ilaria, Pregnolato, Massimo, Terreni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273923/
https://www.ncbi.nlm.nih.gov/pubmed/27898006
http://dx.doi.org/10.3390/molecules21121621