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What Characteristics Confer Proteins the Ability to Induce Allergic Responses? IgE Epitope Mapping and Comparison of the Structure of Soybean 2S Albumins and Ara h 2

Ara h 2, a peanut 2S albumin, is associated with severe allergic reactions, but a homologous protein, soybean 2S albumin, is not recognized as an important allergen. Structural difference between these proteins might explain this clinical discrepancy. Therefore, we mapped sequential epitopes and com...

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Detalles Bibliográficos
Autores principales: Han, Youngshin, Lin, Jing, Bardina, Ludmilla, Grishina, Galina A., Lee, Chaeyoon, Seo, Won Hee, Sampson, Hugh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273924/
https://www.ncbi.nlm.nih.gov/pubmed/27187334
http://dx.doi.org/10.3390/molecules21050622