Antileishmanial Activity and Structure-Activity Relationship of Triazolic Compounds Derived from the Neolignans Grandisin, Veraguensin, and Machilin G

Sixteen 1,4-diaryl-1,2,3-triazole compounds 4–19 derived from the tetrahydrofuran neolignans veraguensin 1, grandisin 2, and machilin G 3 were tested against Leishmania (Leishmania) amazonensis intracellular amastigotes. Triazole compounds 4–19 were synthetized via Click Chemistry strategy by 1,3-di...

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Detalles Bibliográficos
Autores principales: Costa, Eduarda C., Cassamale, Tatiana B., Carvalho, Diego B., Bosquiroli, Lauriane S. S., Ojeda, Mariáh, Ximenes, Thalita V., Matos, Maria F. C., Kadri, Mônica C. T., Baroni, Adriano C. M., Arruda, Carla C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273954/
https://www.ncbi.nlm.nih.gov/pubmed/27331807
http://dx.doi.org/10.3390/molecules21060802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273954/
https://www.ncbi.nlm.nih.gov/pubmed/27331807
http://dx.doi.org/10.3390/molecules21060802

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