Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed anti-inflammatory and pain relief medications. However, their use is associated with many drawbacks, including mainly serious gastric and renal complications. In an attempt to circumvent these risks, a set of N-(4-bromop...

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Detalles Bibliográficos
Autores principales: Gouda, Ahmed M., Ali, Hamed I., Almalki, Waleed H., Azim, Mohamed A., Abourehab, Mohammed A. S., Abdelazeem, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273963/
https://www.ncbi.nlm.nih.gov/pubmed/26867188
http://dx.doi.org/10.3390/molecules21020201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273963/
https://www.ncbi.nlm.nih.gov/pubmed/26867188
http://dx.doi.org/10.3390/molecules21020201

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