Synthesis and Pharmacological Evaluation of Novel Pleuromutilin Derivatives with Substituted Benzimidazole Moieties

A series of novel pleuromutilin derivatives with substituted benzimidazole moieties were designed and synthesized from pleuromutilin and 5-amino-2-mercaptobenzimidazole through sequential reactions. All the newly synthesized compounds were characterized by IR, NMR, and HRMS. Each of the derivatives...

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Detalles Bibliográficos
Autores principales: Ai, Xin, Pu, Xiuying, Yi, Yunpeng, Liu, Yu, Xu, Shuijin, Liang, Jianping, Shang, Ruofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273978/
https://www.ncbi.nlm.nih.gov/pubmed/27834819
http://dx.doi.org/10.3390/molecules21111488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273978/
https://www.ncbi.nlm.nih.gov/pubmed/27834819
http://dx.doi.org/10.3390/molecules21111488

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