Synthesis and in Vitro and in Vivo Anticoagulant and Antiplatelet Activities of Amidino- and Non-Amidinobenzamides

Three amidino- and ten non-amidinobenzamides were synthesized as 3-aminobenzoic acid scaffold-based anticoagulant and antiplatelet compounds. The anticoagulant activities of thirteen synthesized compounds 1–13, and 2b and 3b as prodrugs were preliminary evaluated by screening the prolongation of act...

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Detalles Bibliográficos
Autores principales: Lee, Soo Hyun, Lee, Wonhwa, Bae, Jong-Sup, Ma, Eunsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273990/
https://www.ncbi.nlm.nih.gov/pubmed/27213328
http://dx.doi.org/10.3390/molecules21050676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273990/
https://www.ncbi.nlm.nih.gov/pubmed/27213328
http://dx.doi.org/10.3390/molecules21050676

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