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The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells

Multidrug resistance (MDR) is often attributed to the over-expression of P-glycoprotein (P-gp), which prevents the accumulation of anticancer drugs within cells by virtue of its active drug efflux capacity. We have previously described the intercellular transfer of P-gp via extracellular vesicles (E...

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Detalles Bibliográficos
Autores principales: Pokharel, Deep, Padula, Matthew P., Lu, Jamie F., Jaiswal, Ritu, Djordjevic, Steven P., Bebawy, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273996/
https://www.ncbi.nlm.nih.gov/pubmed/26938523
http://dx.doi.org/10.3390/molecules21030290