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The Search for Covalently Ligandable Proteins in Biological Systems

This commentary highlights the recent article published in Nature, June 2016, titled: “Proteome-wide covalent ligand discovery in native biological systems”. They screened the whole proteome of different human cell lines and cell lysates. Around 700 druggable cysteines in the whole proteome were fou...

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Detalles Bibliográficos
Autores principales: Badshah, Syed Lal, Mabkhot, Yahia Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274003/
https://www.ncbi.nlm.nih.gov/pubmed/27598117
http://dx.doi.org/10.3390/molecules21091170