Interaction of Di-2-pyridylketone 2-pyridine Carboxylic Acid Hydrazone and Its Copper Complex with BSA: Effect on Antitumor Activity as Revealed by Spectroscopic Studies

The drug, di-2-pyridylketone-2-pyridine carboxylic acid hydrazone (DPPCAH) and its copper complex (DPPCAH-Cu) exhibit significant antitumor activity. However, the mechanism of their pharmacological interaction with the biological molecule bovine serum albumin (BSA) remains poorly understood. The pre...

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Detalles Bibliográficos
Autores principales: Li, Cuiping, Huang, Tengfei, Fu, Yun, Liu, Youxun, Zhou, Sufeng, Qi, Zhangyang, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274005/
https://www.ncbi.nlm.nih.gov/pubmed/27136517
http://dx.doi.org/10.3390/molecules21050563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274005/
https://www.ncbi.nlm.nih.gov/pubmed/27136517
http://dx.doi.org/10.3390/molecules21050563

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