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Interaction of Di-2-pyridylketone 2-pyridine Carboxylic Acid Hydrazone and Its Copper Complex with BSA: Effect on Antitumor Activity as Revealed by Spectroscopic Studies
The drug, di-2-pyridylketone-2-pyridine carboxylic acid hydrazone (DPPCAH) and its copper complex (DPPCAH-Cu) exhibit significant antitumor activity. However, the mechanism of their pharmacological interaction with the biological molecule bovine serum albumin (BSA) remains poorly understood. The pre...
Autores principales: | Li, Cuiping, Huang, Tengfei, Fu, Yun, Liu, Youxun, Zhou, Sufeng, Qi, Zhangyang, Li, Changzheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274005/ https://www.ncbi.nlm.nih.gov/pubmed/27136517 http://dx.doi.org/10.3390/molecules21050563 |
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