Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia

Resistance to chemotherapy is a major challenge to improving overall survival in Acute Myeloid Leukemia (AML). Therefore, the development of innovative therapies and the identification of more novel agents for AML are urgently needed. Celastrol, a compound extracted from the Chinese herb Tripterygiu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Xianjun, Ruan, Xuzhi, Zhang, Jingxuan, Zhao, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274014/
https://www.ncbi.nlm.nih.gov/pubmed/27144550
http://dx.doi.org/10.3390/molecules21050574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274014/
https://www.ncbi.nlm.nih.gov/pubmed/27144550
http://dx.doi.org/10.3390/molecules21050574

Ejemplares similares