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Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia

Resistance to chemotherapy is a major challenge to improving overall survival in Acute Myeloid Leukemia (AML). Therefore, the development of innovative therapies and the identification of more novel agents for AML are urgently needed. Celastrol, a compound extracted from the Chinese herb Tripterygiu...

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Detalles Bibliográficos
Autores principales:	Yu, Xianjun, Ruan, Xuzhi, Zhang, Jingxuan, Zhao, Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274014/ https://www.ncbi.nlm.nih.gov/pubmed/27144550 http://dx.doi.org/10.3390/molecules21050574

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