Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin

Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. During the process development of linagliptin, five new process-related impurities were detected by high performance liquid chromatography (HPL...

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Detalles Bibliográficos
Autores principales: Huang, Yiwen, He, Xiaoqing, Wu, Taizhi, Zhang, Fuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274017/
https://www.ncbi.nlm.nih.gov/pubmed/27517889
http://dx.doi.org/10.3390/molecules21081041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274017/
https://www.ncbi.nlm.nih.gov/pubmed/27517889
http://dx.doi.org/10.3390/molecules21081041

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