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The Chiral Pool in the Pictet–Spengler Reaction for the Synthesis of β-Carbolines
The Pictet–Spengler reaction (PSR) is the reaction of a β-arylethylamine with an aldehyde or ketone, followed by ring closure to give an aza-heterocycle. When the β-arylethylamine is tryptamine, the product is a β-carboline, a widespread skeleton in natural alkaloids. In the natural occurrence, thes...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274020/ https://www.ncbi.nlm.nih.gov/pubmed/27240334 http://dx.doi.org/10.3390/molecules21060699 |