Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis

Our previous work has described a library of thioxanthones designed to have dual activity as P-glycoprotein modulators and antitumor agents. Some of these compounds had shown a significant cell growth inhibitory activity towards leukemia cell lines, without affecting the growth of non-tumor human fi...

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Detalles Bibliográficos
Autores principales: Barbosa, João, Lima, Raquel T., Sousa, Diana, Gomes, Ana Sara, Palmeira, Andreia, Seca, Hugo, Choosang, Kantima, Pakkong, Pannee, Bousbaa, Hassan, Pinto, Madalena M., Sousa, Emília, Vasconcelos, M. Helena, Pedro, Madalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274047/
https://www.ncbi.nlm.nih.gov/pubmed/26771595
http://dx.doi.org/10.3390/molecules21010081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274047/
https://www.ncbi.nlm.nih.gov/pubmed/26771595
http://dx.doi.org/10.3390/molecules21010081

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