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Inhibition of Urease by Disulfiram, an FDA-Approved Thiol Reagent Used in Humans

Urease is a nickel-dependent amidohydrolase that catalyses the decomposition of urea into carbamate and ammonia, a reaction that constitutes an important source of nitrogen for bacteria, fungi and plants. It is recognized as a potential antimicrobial target with an impact on medicine, agriculture, a...

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Detalles Bibliográficos
Autores principales: Díaz-Sánchez, Ángel Gabriel, Alvarez-Parrilla, Emilio, Martínez-Martínez, Alejandro, Aguirre-Reyes, Luis, Orozpe-Olvera, Jesica Aline, Ramos-Soto, Miguel Armando, Núñez-Gastélum, José Alberto, Alvarado-Tenorio, Bonifacio, de la Rosa, Laura Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274061/
https://www.ncbi.nlm.nih.gov/pubmed/27898047
http://dx.doi.org/10.3390/molecules21121628