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Neuroprotection by Combined Administration with Maslinic Acid, a Natural Product from Olea europaea, and MK-801 in the Cerebral Ischemia Model

Glutamate-mediated excitotoxicity is a major cause of ischemic brain damage. MK-801 confers neuroprotection by attenuating the activation of the N-methyl-d-aspartate (NMDA) receptor, but it failed in clinical use due to the short therapeutic window. Here we aim to investigate the effects of maslinic...

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Detalles Bibliográficos
Autores principales: Qian, Yisong, Tang, Xuzhen, Guan, Teng, Li, Yunman, Sun, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274070/
https://www.ncbi.nlm.nih.gov/pubmed/27548129
http://dx.doi.org/10.3390/molecules21081093