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Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety

A series of novel hybrid compounds between benzofuran and N-aryl piperazine have been synthesized and screened in vitro for anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW-264.7 macrophages and for anticancer activity against three human tumor cell lines. The results demonstrat...

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Detalles Bibliográficos
Autores principales: Ma, Yulu, Zheng, Xi, Gao, Hui, Wan, Chunping, Rao, Gaoxiong, Mao, Zewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274084/
https://www.ncbi.nlm.nih.gov/pubmed/27941680
http://dx.doi.org/10.3390/molecules21121684