Evaluation and Comparison of the Inhibition Effect of Astragaloside IV and Aglycone Cycloastragenol on Various UDP-Glucuronosyltransferase (UGT) Isoforms

As one of the main active ingredients from Radix Astragali (RA), orally dosed astragaloside IV (AST) is easily transformed to sapogenin-cycloastragenol (CAG) by deglycosylation in the gastrointestinal tract. Because the potential adverse effects of AST and CAG remain unclear, the present study in th...

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Detalles Bibliográficos
Autores principales: Ran, Ruixue, Zhang, Chunze, Li, Rongshan, Chen, Bowei, Zhang, Weihua, Zhao, Zhenying, Fu, Zhiwei, Du, Zuo, Du, Xiaolang, Yang, Xiaolong, Fang, Zhongze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274106/
https://www.ncbi.nlm.nih.gov/pubmed/27916843
http://dx.doi.org/10.3390/molecules21121616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274106/
https://www.ncbi.nlm.nih.gov/pubmed/27916843
http://dx.doi.org/10.3390/molecules21121616

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