Development of an Innovative Intradermal siRNA Delivery System Using a Combination of a Functional Stearylated Cytoplasm-Responsive Peptide and a Tight Junction-Opening Peptide

As a new category of therapeutics for skin diseases including atopic dermatitis (AD), nucleic acids are gaining importance in the clinical setting. Intradermal administration is noninvasive and improves patients′ quality of life. However, intradermal small interfering RNA (siRNA) delivery is difficu...

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Detalles Bibliográficos
Autores principales: Ibaraki, Hisako, Kanazawa, Takanori, Takashima, Yuuki, Okada, Hiroaki, Seta, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274127/
https://www.ncbi.nlm.nih.gov/pubmed/27669207
http://dx.doi.org/10.3390/molecules21101279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274127/
https://www.ncbi.nlm.nih.gov/pubmed/27669207
http://dx.doi.org/10.3390/molecules21101279

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