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An Ingenol Derived from Euphorbia kansui Induces Hepatocyte Cytotoxicity by Triggering G0/G1 Cell Cycle Arrest and Regulating the Mitochondrial Apoptosis Pathway in Vitro

Natural product lingenol, a purified diterpenoid compound derived from the root of Euphorbia kansui, exerts serious hepatotoxicity; however, the molecular mechanisms remain to be defined. In the present study, cell counting Kit-8 (CCK-8), inverted phase contrast microscope and flow cytometry were us...

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Detalles Bibliográficos
Autores principales:	Yan, Xiaojing, Zhang, Li, Cao, Yudan, Yao, Weifeng, Tang, Yuping, Ding, Anwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274136/ https://www.ncbi.nlm.nih.gov/pubmed/27338329 http://dx.doi.org/10.3390/molecules21060813

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