Rosmarinic Acid Methyl Ester Inhibits LPS-Induced NO Production via Suppression of MyD88- Dependent and -Independent Pathways and Induction of HO-1 in RAW 264.7 Cells

In this study, we investigated the anti-inflammatory effect of rosmarinic acid methyl ester (RAME) isolated from a mutant cultivar of Perilla frutescens (L.) Britton. We found that RAME inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production, with an IC(50) of 14.25 µM, in RAW 264.7 c...

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Detalles Bibliográficos
Autores principales: So, Yangkang, Lee, Seung Young, Han, Ah-Reum, Kim, Jin-Baek, Jeong, Hye Gwang, Jin, Chang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274143/
https://www.ncbi.nlm.nih.gov/pubmed/27548124
http://dx.doi.org/10.3390/molecules21081083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274143/
https://www.ncbi.nlm.nih.gov/pubmed/27548124
http://dx.doi.org/10.3390/molecules21081083

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