In Vitro Neuroprotective and Anti-Inflammatory Activities of Natural and Semi-Synthetic Spirosteroid Analogues

Two spirosteroid analogues were synthesized and evaluated for their in vitro neuroprotective activities in PC12 cells, against glutamate-induced excitotoxicity and mitochondrial damage in glucose deprivation conditions, as well as their anti-inflammatory potential in LPS/IFNγ-stimulated microglia pr...

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Detalles Bibliográficos
Autores principales: García-Pupo, Laura, Zaldo-Castro, Armando, Exarchou, Vassiliki, Tacoronte-Morales, Juan Enrique, Pieters, Luc, Vanden Berghe, Wim, Nuñez-Figueredo, Yanier, Delgado-Hernández, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274191/
https://www.ncbi.nlm.nih.gov/pubmed/27483221
http://dx.doi.org/10.3390/molecules21080992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274191/
https://www.ncbi.nlm.nih.gov/pubmed/27483221
http://dx.doi.org/10.3390/molecules21080992

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