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Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function. In this paper, the UPLC-TQ/MS method of simultaneously determining four tanshinones—tanshinone IIA, dihydrotanshinone I, ta...

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Detalles Bibliográficos
Autores principales: Cai, Hong-Die, Su, Shu-Lan, Li, Yonghui, Zhu, Zhenhua, Guo, Jianming, Zhu, Yue, Guo, Sheng, Qian, Dawei, Duan, Jinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274205/
https://www.ncbi.nlm.nih.gov/pubmed/27916808
http://dx.doi.org/10.3390/molecules21121630