Synthesis, Biological Evaluation and Molecular Docking Studies of 6-Aryl-2-Styrylquinazolin-4(3H)-Ones

Suzuki-Miyaura cross-coupling of 6-bromo-2-styrylquinazolin-4(3H)-ones with arylboronic acids afforded a series of novel 6-aryl-2-styrylquinazolin-4(3H)-ones. These compounds were evaluated for potential anticancer properties against the human renal (TK-10), melanoma (UACC-62) and breast cancer (MCF...

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Detalles Bibliográficos
Autores principales: Agbo, Emmanuel Ndubuisi, Makhafola, Tshepiso Jan, Choong, Yee Siew, Mphahlele, Malose Jack, Ramasami, Ponnadurai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274206/
https://www.ncbi.nlm.nih.gov/pubmed/26712730
http://dx.doi.org/10.3390/molecules21010028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274206/
https://www.ncbi.nlm.nih.gov/pubmed/26712730
http://dx.doi.org/10.3390/molecules21010028

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