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Mono-PEGylation of Alpha-MMC and MAP30 from Momordica charantia L.: Production, Identification and Anti-Tumor Activity

PEGylation is a well-established and effective strategy to decrease immunogenicity, which can increase the stability and in vivo half-life time. However, the generation of multi-site modified products is inevitable due to the lysine chemistry, which will bring difficulties in subsequent research, su...

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Detalles Bibliográficos
Autores principales: Sun, Yun, Sun, Fenghui, Li, Jianlong, Wu, Minlu, Fan, Xiang, Meng, Yanfa, Meng, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274223/
https://www.ncbi.nlm.nih.gov/pubmed/27809255
http://dx.doi.org/10.3390/molecules21111457