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Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1

A new CYP26A1 homology model was built based on the crystal structure of cyanobacterial CYP120A1. The model quality was examined for stereochemical accuracy, folding reliability, and absolute quality using a variety of different bioinformatics tools. Furthermore, the docking capabilities of the mode...

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Detalles Bibliográficos
Autores principales: Awadalla, Mohamed K. A., Alshammari, Thamir M., Eriksson, Leif A., Saenz-Méndez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274249/
https://www.ncbi.nlm.nih.gov/pubmed/26999080
http://dx.doi.org/10.3390/molecules21030351