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Regioselective Palmitoylation of 9-(2,3-Dihydroxy- propyl)adenine Catalyzed by a Glycopolymer-enzyme Conjugate
The enzymatic regioselective monopalmitoylation of racemic 9-(2,3-dihydroxypropyl)- adenine (DHPA), an approved antiviral agent, has been performed by an immobilized form of Candida antarctica B lipase (CAL-B) using a 4:1 DMF/hexane mixture as the reaction medium. To improve the chemical yield of th...
Autores principales: | Brabcová, Jana, Blažek, Jiří, Krečmerová, Marcela, Vondrášek, Jiří, Palomo, Jose M., Zarevúcka, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274252/ https://www.ncbi.nlm.nih.gov/pubmed/27196879 http://dx.doi.org/10.3390/molecules21050648 |
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