New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells

The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as reference compound. The results revealed that...

Descripción completa

Detalles Bibliográficos
Autores principales: Malki, Ahmed, Mohsen, Mona, Aziz, Hassan, Rizk, Ola, Shaaban, Omaima, El-Sayed, Mohamed, Sherif, Zaki A., Ashour, Hayam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274259/
https://www.ncbi.nlm.nih.gov/pubmed/26901182
http://dx.doi.org/10.3390/molecules21020230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274259/
https://www.ncbi.nlm.nih.gov/pubmed/26901182
http://dx.doi.org/10.3390/molecules21020230

Ejemplares similares