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Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates

Based on the presence of carbamoyl moiety, twenty salicylanilide N,N-disubstituted (thio)carbamates were investigated using Ellman’s method for their ability to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). O-Aromatic (thio)carbamates exhibited weak to moderate inhibition of...

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Detalles Bibliográficos
Autores principales: Krátký, Martin, Štěpánková, Šárka, Vorčáková, Katarína, Švarcová, Markéta, Vinšová, Jarmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274279/
https://www.ncbi.nlm.nih.gov/pubmed/26875979
http://dx.doi.org/10.3390/molecules21020191