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Synthesis and Anti-Tumor Activities of 4-Anilinoquinoline Derivatives

Twenty-two 7-fluoro (or 8-methoxy)-4-anilinoquinolines compounds were designed and synthesized as potentially potent and selective antitumor inhibitors. All the prepared compounds were evaluated for their in vitro antiproliferative activities against the HeLa and BGC823 cell lines. Ten compounds (1a...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Luan, Tian, Kong, Jian, Zhang, Ying, Wang, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274288/
https://www.ncbi.nlm.nih.gov/pubmed/26703559
http://dx.doi.org/10.3390/molecules21010021