Synthesis of Pyrazole-Thiobarbituric Acid Derivatives: Antimicrobial Activity and Docking Studies

A one-pot reaction was described that results in various pyrazole-thiobarbituric acid derivatives as new pharmacophore agents. These new heterocycles were synthesized in high yields with a broad substrate scope under mild reaction conditions in water mediated by NHEt(2). The molecular structures of...

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Detalles Bibliográficos
Autores principales: Elshaier, Yaseen A. M. M., Barakat, Assem, Al-Qahtany, Bander M., Al-Majid, Abdullah Mohammed, Al-Agamy, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274314/
https://www.ncbi.nlm.nih.gov/pubmed/27735850
http://dx.doi.org/10.3390/molecules21101337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274314/
https://www.ncbi.nlm.nih.gov/pubmed/27735850
http://dx.doi.org/10.3390/molecules21101337

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