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Synthesis and Pharmacological Evaluation of Novel 1-(1,4-Alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted Urea Derivatives

Novel 1-(1,4-alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted urea derivatives have been synthesized and evaluated for their central nervous system activity. Compounds 3a–m were prepared in the reaction between the respective 1-alkyl-4-aryl-4,5-dihydro-1H-imidazol-2-amines 1a–c and appro...

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Detalles Bibliográficos
Autores principales: Szacoń, Elżbieta, Rządkowska, Marzena, Kaczor, Agnieszka A., Kędzierska, Ewa, Orzelska-Górka, Jolanta, Fidecka, Sylwia, Matosiuk, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274338/
https://www.ncbi.nlm.nih.gov/pubmed/27144554
http://dx.doi.org/10.3390/molecules21050582