Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives

The search for new molecular constructs that resemble the critical two-metal binding pharmacophore and the halo-substituted phenyl functionality required for HIV-1 integrase (IN) inhibition represents a vibrant area of research within drug discovery. As reported herein, we have modified our recently...

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Detalles Bibliográficos
Autores principales: Liu, Guan-Nan, Luo, Rong-Hua, Zhou, Yu, Zhang, Xing-Jie, Li, Jian, Yang, Liu-Meng, Zheng, Yong-Tang, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274355/
https://www.ncbi.nlm.nih.gov/pubmed/27617994
http://dx.doi.org/10.3390/molecules21091198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274355/
https://www.ncbi.nlm.nih.gov/pubmed/27617994
http://dx.doi.org/10.3390/molecules21091198

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