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New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles

Intravenous administration of Taxotere(®) (a commercial form of docetaxel, DTX) leads to many problems such as hypersensitivity, hemolysis, cutaneous allergy, and patient refusal due to its prolonged injection. The oral absorption of DTX is very low due to its hydrophobic nature. The purpose of this...

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Detalles Bibliográficos
Autores principales: Hekmat, Atefeh, Attar, Hossein, Seyf Kordi, Ali Akbar, Iman, Maryam, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274371/
https://www.ncbi.nlm.nih.gov/pubmed/27657038
http://dx.doi.org/10.3390/molecules21091265