A Modular Synthetic Approach to Isosteric Sulfonic Acid Analogues of the Anticoagulant Pentasaccharide Idraparinux

Heparin-based anticoagulants are drugs of choice in the therapy and prophylaxis of thromboembolic diseases. Idraparinux is a synthetic anticoagulant pentasaccharide based on the heparin antithrombin-binding domain. In the frame of our ongoing research aimed at the synthesis of sulfonic acid-containi...

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Detalles Bibliográficos
Autores principales: Mező, Erika, Eszenyi, Dániel, Varga, Eszter, Herczeg, Mihály, Borbás, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274384/
https://www.ncbi.nlm.nih.gov/pubmed/27845725
http://dx.doi.org/10.3390/molecules21111497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274384/
https://www.ncbi.nlm.nih.gov/pubmed/27845725
http://dx.doi.org/10.3390/molecules21111497

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