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Synthesis and Biological Evaluation of Novel (99m)Tc(CO)(3)-Labeled Thymidine Analogs as Potential Probes for Tumor Proliferation Imaging
Achieving a (99m)Tc labeled thymidine radiotracer for single photon emission tomography (SPECT) is considered to be of interest. In this study, four novel thymidine analogs, 6a, 6b, 6c and 6d, were successfully synthesized via “click reaction” route and then radiolabeled using a [(99m)Tc(CO)(3)](+)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274394/ https://www.ncbi.nlm.nih.gov/pubmed/27104501 http://dx.doi.org/10.3390/molecules21040510 |