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Synthesis and Biological Evaluation of Novel (99m)Tc(CO)(3)-Labeled Thymidine Analogs as Potential Probes for Tumor Proliferation Imaging

Achieving a (99m)Tc labeled thymidine radiotracer for single photon emission tomography (SPECT) is considered to be of interest. In this study, four novel thymidine analogs, 6a, 6b, 6c and 6d, were successfully synthesized via “click reaction” route and then radiolabeled using a [(99m)Tc(CO)(3)](+)...

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Detalles Bibliográficos
Autores principales: Duan, Xiaojiang, Liu, Teli, Zhang, Yichun, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274394/
https://www.ncbi.nlm.nih.gov/pubmed/27104501
http://dx.doi.org/10.3390/molecules21040510