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Alisol F 24 Acetate Enhances Chemosensitivity and Apoptosis of MCF-7/DOX Cells by Inhibiting P-Glycoprotein-Mediated Drug Efflux

Multidrug resistance (MDR) is a prime reason for numerous failed oncotherapy approaches. In the present study, we investigated whether Alisol F 24 acetate (ALI) could reverse the MDR of MCF-7/DOX cells, a multidrug-resistant human breast cancer cell line. We found that ALI was a potent P-glycoprotei...

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Detalles Bibliográficos
Autores principales: Pan, Guixiang, Li, Tingting, Zeng, Qingqing, Wang, Xiaoming, Zhu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274399/
https://www.ncbi.nlm.nih.gov/pubmed/26861264
http://dx.doi.org/10.3390/molecules21020183