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Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents

Several new pyrazole, pyridine, [1,2,4]triazolo[1,5-α]pyrimidine, benzimidazo[1,2-a]pyrimidine and 1,2,4-triazolo[3,4-c][1,2,4]triazine derivatives incorporating a thiophene moiety were synthesized from (E)-ethyl 5-(3-(dimethylamino)acryloyl)-4-phenyl-2-(phenylamino)thiophene-3-carboxylate (1). The...

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Detalles Bibliográficos
Autores principales: Mabkhot, Yahia Nasser, Alatibi, Fatima, El-Sayed, Nahed Nasser E., Kheder, Nabila Abdelshafy, Al-Showiman, Salim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274416/
https://www.ncbi.nlm.nih.gov/pubmed/27517888
http://dx.doi.org/10.3390/molecules21081036