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Synthesis and Anticancer Activities of Glycyrrhetinic Acid Derivatives

A total of forty novel glycyrrhetinic acid (GA) derivatives were designed and synthesized. The cytotoxic activity of the novel compounds was tested against two human breast cancer cell lines (MCF-7, MDA-MB-231) in vitro by the MTT method. The evaluation results revealed that, in comparison with GA,...

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Detalles Bibliográficos
Autores principales: Li, Yang, Feng, Ling, Song, Zhi-Fang, Li, Hai-Bei, Huai, Qi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274419/
https://www.ncbi.nlm.nih.gov/pubmed/26861280
http://dx.doi.org/10.3390/molecules21020199