Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents

New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...

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Detalles Bibliográficos
Autores principales: Liu, Da-Chuan, Zhang, Hong-Jian, Jin, Chun-Mei, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274423/
https://www.ncbi.nlm.nih.gov/pubmed/26938519
http://dx.doi.org/10.3390/molecules21030164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274423/
https://www.ncbi.nlm.nih.gov/pubmed/26938519
http://dx.doi.org/10.3390/molecules21030164

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