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Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents
New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...
Autores principales: | Liu, Da-Chuan, Zhang, Hong-Jian, Jin, Chun-Mei, Quan, Zhe-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274423/ https://www.ncbi.nlm.nih.gov/pubmed/26938519 http://dx.doi.org/10.3390/molecules21030164 |
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