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Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy

Ursolic acid (UA), a naturally occurring pentacyclic triterpene acid found in many medicinal herbs and edible plants, triggers apoptosis in several tumor cell lines but not in human bone cancer cells. Most recently, we have demonstrated that UA exposure reduces the viability of human osteosarcoma MG...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Chieh, Huang, Yi-Fu, Hsieh, Chen-Pu, Chueh, Pin-Ju, Chen, Yao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274426/
https://www.ncbi.nlm.nih.gov/pubmed/27916903
http://dx.doi.org/10.3390/molecules21121640