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Ligand Fishing: A Remarkable Strategy for Discovering Bioactive Compounds from Complex Mixture of Natural Products

Identification of active compounds from natural products is a critical and challenging task in drug discovery pipelines. Besides commonly used bio-guided screening approaches, affinity selection strategy coupled with liquid chromatography or mass spectrometry, known as ligand fishing, has been gaini...

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Detalles Bibliográficos
Autores principales: Zhuo, Rongjie, Liu, Hao, Liu, Ningning, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274472/
https://www.ncbi.nlm.nih.gov/pubmed/27845727
http://dx.doi.org/10.3390/molecules21111516