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Native Mass Spectrometry in Fragment-Based Drug Discovery

The advent of native mass spectrometry (MS) in 1990 led to the development of new mass spectrometry instrumentation and methodologies for the analysis of noncovalent protein–ligand complexes. Native MS has matured to become a fast, simple, highly sensitive and automatable technique with well-establi...

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Detalles Bibliográficos
Autores principales: Pedro, Liliana, Quinn, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274484/
https://www.ncbi.nlm.nih.gov/pubmed/27483215
http://dx.doi.org/10.3390/molecules21080984