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Native Mass Spectrometry in Fragment-Based Drug Discovery
The advent of native mass spectrometry (MS) in 1990 led to the development of new mass spectrometry instrumentation and methodologies for the analysis of noncovalent protein–ligand complexes. Native MS has matured to become a fast, simple, highly sensitive and automatable technique with well-establi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274484/ https://www.ncbi.nlm.nih.gov/pubmed/27483215 http://dx.doi.org/10.3390/molecules21080984 |