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Synthesis, Biological Evaluation and Molecular Docking of Certain Sulfones as Potential Nonazole Antifungal Agents

We reported herein the synthesis, antifungal activity, docking and in silico ADME prediction studies of four novel series of sulfones 6a–f, 8a–c, 10a–f and 12a–c. All the newly synthesized sulfones were tested against four strains of Candida (including fluconazole-resistant Candida), two strains of...

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Detalles Bibliográficos
Autores principales: Fares, Mohamed, Said, Mohamed A., Alsherbiny, Muhammad A., Eladwy, Radwa A., Almahli, Hadia, Abdel-Aziz, Marwa M., Ghabbour, Hazem A., Eldehna, Wagdy M., Abdel-Aziz, Hatem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274496/
https://www.ncbi.nlm.nih.gov/pubmed/26805791
http://dx.doi.org/10.3390/molecules21010114