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LC-MS/MS Analysis and Pharmacokinetics of Sodium (±)-5-Bromo-2-(α-hydroxypentyl) Benzoate (BZP), an Innovative Potent Anti-Ischemic Stroke Agent in Rats

A rapid, sensitive and selective liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous determination of sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (BZP) and its active metabolite 3-butyl-6-bromo-1(3H)-isobenzofuranone (Br-NB...

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Detalles Bibliográficos
Autores principales: Tian, Xin, Liu, Bingjie, Zhang, Yuhai, Li, Hongmeng, Wei, Jingyao, Wang, Gaoju, Chang, Junbiao, Qiao, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274500/
https://www.ncbi.nlm.nih.gov/pubmed/27092484
http://dx.doi.org/10.3390/molecules21040501