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LC-MS/MS Analysis and Pharmacokinetics of Sodium (±)-5-Bromo-2-(α-hydroxypentyl) Benzoate (BZP), an Innovative Potent Anti-Ischemic Stroke Agent in Rats
A rapid, sensitive and selective liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous determination of sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (BZP) and its active metabolite 3-butyl-6-bromo-1(3H)-isobenzofuranone (Br-NB...
Autores principales: | Tian, Xin, Liu, Bingjie, Zhang, Yuhai, Li, Hongmeng, Wei, Jingyao, Wang, Gaoju, Chang, Junbiao, Qiao, Hailing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274500/ https://www.ncbi.nlm.nih.gov/pubmed/27092484 http://dx.doi.org/10.3390/molecules21040501 |
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